Archive for February, 2008

Human BPA contamination is confirmed by study

admin February 28th, 2008

I read this today in the peer-reviewed journal “Science”

“SHINY, PLASTIC PEOPLE
You may already be a part of Ken and Barbie’s plastic family. A new U.S. government study suggests that the bodies of most Americans are laced with bisphenol A (BPA), the primary component of one of the most widely used plastics.

BPA is an ingredient in polycarbonate plastics, used in everything from baby bottles to composite dental fillings to toy dolls. Frequent use and heating can cause the plastic to break down, leaching BPA into whatever the plastic touches, including food. Although recent studies have linked BPA to reproductive problems in lab animals, little is known about humans and BPA.

To measure BPA exposure, chemist Antonia Calafat and colleagues at the U.S. Centers for Disease Control and Prevention in Atlanta, Georgia, examined urine samples from 2517 participants in the ongoing National Health and Nutrition Examination Survey. Significant levels of BPA were present in 92% of the samples. Those with the highest levels were children and adolescents, women, and low-income participants.

The body metabolizes BPA in only a few hours, suggesting that exposure to BPA is continuous, says epidemiologist Russ Hauser of Harvard School of Public Health in Boston. Although the jury’s still out on what high exposures mean for human health, Hauser says industry should consider alternatives that aren’t biologically active.”

I had heard several mentions about BPA in the blogosphere, but I had wondered if this was perhaps a case of people becoming alarmed at something that was not truly of concern. Perhaps the amounts of this stuff were very small. Perhaps we weren’t really absorbing it. To my knowledge, previous studies have been conducted in animals, and while this information is very useful, animal models do not always correlate well with human biology. Well now they have found this stuff in people. It appears that this is a real phenomenon. Of course, as the article says, we don’t have a firm handle on what this means to human health, these findings are truly alarming.

If you would like to read some very thoughtful writing on this subject that includes information on how to remove BPA leaching products from your home, I highly recommend a post by Michelle at mihow.com.

http://mihow.com/articles/2008/1/28/waging-war-against-bisphenol-a

Retrospective on the gender of my baby

admin February 27th, 2008

I was wishing for a little girl. They are so cute in their funky clothes, and pigtails. I was going to teach her how to be strong and fierce and not bend to pressure to be someone she wasn’t. I was going to show her how she could be feminine, but not weak. I would buy her trucks and tools and no one was going to tell her that anything was wrong with that. She was going to be one incredible woman. The one every man wanted. The one every woman wanted to be.

And then I learned she had a penis. She was a he. And I knew this was a possibility. And I had told myself I didn’t care. And I really was very excited to see him and just to know more about that baby in there. But after the adrenaline of the ultrasound, I have to admit I was a little sad. I really don’t think I should put his hair in pigtails. Rough and tumble play will be “normal” for him. And I mourned the possibility of a daughter a little. I’ll admit it.

But now, I am so excited! I finally know what people mean when they talk of wanting to finally meet their little baby. I just can’t wait to see him. He will be an awesome little boy. We will have so much fun, and I will get to experience a dozen things that I wasn’t privy to as a girl. The high school years should hopefully be easier on him. He will be a wonderful beautiful man, just like the one I married and adore. He will look so cute in his little boy clothes – the ones I like anyway. I will show him how to be masculine, but not cruel. I will buy him trucks and tools and an easy bake oven because men should be able to cook just as much as any woman. He will be one incredible man. The one every woman wants. The one every man wishes to be.

I am having a son, and I couldn’t be happier. Dude, I’m having a son.

On paint fumes in pregnancy

admin February 27th, 2008

I was hard at work not writing my thesis earlier today when I happened upon a message board with women discussing the potential dangers of painting their nursery. Since I am somewhat qualified to address this subject, I think I will do it here. BUT I am no MD.

Summary: Latex probably OK. Oil based probably should be avoided. Headache, dizziness, nausea, fatigue - bad.

In general, Latex paints are considered safe. As far as I know, no comprehensive studies have been done on the effects of latex paint on pregnancy, but so many women do it without complications that doctors tend not to think of these paints as a real risk.

Parents should try to paint the nursery at least one month (more if possible) before the baby’s arrival to ensure that most of the fumes (or VOCs = volatile organic compounds) have evaporated and left. Many companies are coming out with low VOC paint. I will definitely check these out when I go to paint my nursery. I hear that they are offered by Home Depot, Lowes, and Sherwin Williams, to name a few. These paints are great because they both reduce the VOCs that the mother breathes and any residual fumes left over in the room once the baby is there. Some people believe that regular paint can continue to give off VOCs for months after the initial application. What they tell us in the lab is to “minimize exposure.” This means, if someone else is willing to do it all, let them. If not, make sure that the room and the areas around it get plenty of ventilation.

Some doctors aren’t too worried about oil based paints and stains, but I am. I know what goes into these things, and what comes out. Some of these chemicals are ones that I have been warned to stay away from in the lab. Many of them are much more potentially harmful than ethanol (drinking alcohol). If alcohol is to be avoided in pregnancy, then certainly I think these chemicals should be too. If one MUST be around for staining or using oils, make sure that every possible means of ventilation is being used, and you are out of the house as much as possible. I would certainly not do this kind of work with an infant around. If you can smell it, you are breathing it. If you don’t smell it, you still may be breathing it.

Now, the take home message. The number one thing we learn in the lab is to listen to our body’s cues. Headache is one of the first signs of overexposure. If what you are doing is giving you a headache, you should stop. If you are staining and you develop a headache, take a break and get out of there. If you must go back, stay for a shorter period and try further measures to reduce exposure. The other cues include dizziness, nausea, and fatigue. These are signs that your body is sick when you are using chemicals. Do not ignore them.

The same advice goes for other potentially harmful but unknown chemicals. If dyeing your hair gives you a headache, then I would advise against doing this during pregnancy. If the pest control guy comes over and you get dizzy, go outside. So much is unknown about the affects of common household chemicals on fetal development. Take cues for your own body. Even if the baby is fine, knowing what makes you sick is a good first start.

Of course there are several other common sources of VOCs in the average house. Some of these include vinyl shower curtains, chemicals in furniture, etc. I need do more reading on these to have any kind of informed opinion. Keep in mind that VOCs are not created equal. An “organic compound” can be most anything, so just because the VOCs in say paint, might be proven innocuous, the VOCs in some other material may not be.

Happy painting!

So

admin February 26th, 2008

It’s a boy! I am so excited.

I can feel him kicking around in there too. It’s similar to The Alien movie, just without all the bursting out, and acid blood and getting eaten. I really don’t understand how some people can not realize they are pregnant. What do they think is bumping around in there? A really big tapeworm? The weirdest gas they’ve ever had?

On Publication Attribution

admin February 14th, 2008

I am wondering what to do about a little situation I am having. Last year a colleague of mine did some experiments that yielded interesting data. He asked me to do some analysis of the data, which I did. Soon thereafter he became more focused on writing and defending his thesis and finding a job, which he did.

Because he was busy with his job and I was already acquainted with his work, he, my adviser and I decided that I would continue this work to make a publishable document. My colleague had designed and implemented the experiments and collected some of the data. I finished up by collecting much more data, analyzing most of the data, and reading and thinking to figure out what was going on and how it fit into the rest of the relevant literature. My colleague had written a few loose paragraphs, but I wrote almost the entire paper.

It comes time to submit for publication and we all decided that the two of us would share authorship. His name would be first, but I could also be considered “first author” and this would be noted on the paper.

Several months pass, the paper is reviewed and lightly revised, and the journal sends me a draft for final review. Nowhere at the top of the paper is my equal contribution noted. (Normally, this is done with asterisks by each name and a note at the bottom of the first page.) The top header does not have my name, and says only “theguy et al.” At the very bottom of the very last page after acknowledgments to the funding agencies, there is a note that GUY and PA shared equal contribution. (The draft we sent them had the asterisks and the note on the first page. This has been deleted entirely.) I mentioned this to my PI who sent them an email back asking that my contribution be at least noted at the top header, so that it would read Theguy and P.Anecdotal et al.

Today being so incredibly bored that I googled myself, I find that this paper has been posted online prior to its final hard copy publication later. Great! I bring it up, and these changes have not been made. The only note of my equal contribution is still that very difficult to find line at the very bottom of the last page.

With as much attention as proper author attribution has received lately, you would think that a journal would bend over backwards to make sure these things are correct. I know some journal policies now make you state exactly what every author contributed, and this is then printed. It just bugs me that they completely ignored our attempts to make note of my contribution.

So, what do I do? Should I just not worry about this? Should I mention it to my PI? Can the journal even do anything at this point?

On Early Gender Stereotyping

admin February 7th, 2008

Gender stereotyping starts early, and can have detrimental, long lasting effects.

Studies have shown that gender stereotyping often begins even before the birth of the child. Prior to learning sex, parents describe their unborn children with roughly the same adjectives, but after learning gender, parents of boys are more likely to use words like “vigorous,” “strong,” and “boisterous” whereas female babies are likely described as “sweet,” or “fussy.” Of course these differences last long after the baby is born.

According to an article in Sex Roles: A Journal of Research, Jan, 1999 by C. Estelle Campenni,
“…parents describe their newborns differentially with girls being described with respect to their appearance while boys are portrayed with respect to their physical abilities.”

These trends are repeated over and over in the clothes children are dressed in, how their rooms are decorated, how they are treated, and the toys they are given.

From Avoiding Gender Stereotypes By Kristen Finello on Parents.com
“Go into a department store, for example, and you’ll notice that the girls’ clothing section is three times the size of the boys.” And girls’ clothing is often pink and less conducive to rough and tumble play,” notes Dr. Crowley-Long. The message: Appearance is critical for girls and they should avoid activities that might “mess up” their cute outfit. Boys, too, are affected by gender stereotypes. In fact, it’s more acceptable for a girl to be a “tomboy” than for a boy to show any effeminate qualities…Stereotypes like this can prevent boys from developing softer elements of their personality that can benefit them as human beings.”

And again from Sex Roles: A Journal of Research, Jan, 1999 by C. Estelle Campenni
“Parental toy choices and child-parent interactions with toys send a clear message to children regarding gender-typed behaviors (Caldera, Huston, O’Brien, 1989). Langolis and Downs (1980) have shown that parents play with their child’s gender-same toys longer, react more positively to gender-same toys, and are more critical of cross-sexed toys. These researchers have also shown that fathers use toys, perhaps unintentionally, to socialize their children differently based on sex and there is evidence that this gender-based socialization process begins as early as the first year of the child’s life (Snow, Jacklin, & Maccobby, 1983)….”

“Gender stereotyping of children’s toys may influence the development of gender schematic role identity in children and may play a part in the differences noted in the cognitive and social skills of girls and boys. Miller (1987) has noted that toys viewed as more appropriate for girls were also rated as attractive, creative, nurturing, and manipulable while masculine toys were identified as more competitive, aggressive, constructive, conducive to handling, encouraging sociability, and reality based. Interestingly, these differences in functionality of gender stereotyped toys correspond to differences noted in the stereotyped feminine and masculine behavioral and personality patterns with stereotypical feminine characteristics described as emotional, gentle, understanding, and creative while masculine traits include aggressive, active, dominant, and competitive (Spence & Helmreich, 1978). In support of the influence of these functional differences on children’s cognitive development, research has found that play with masculine toys may be linked with higher visual-spatial ability while play with feminine toys may be related to higher vocabulary ability (Serbin & Connor, 1979; Tracy, 1987).”

From Parental Influence on Children’s Socialization to Gender Roles, Adolescence, Summer, 1997Susan D. Witt, Ph.D, University of Akron, School of Home Economics and Family Ecology
“Parental attitudes towards their children have a strong impact on the child’s developing sense of self and self-esteem, with parental warmth and support being key factors for the child (Richards, Gitelson, Petersen, & Hartig, 1991). Often, parents give subtle messages regarding gender and what is acceptable for each gender - messages that are internalized by the developing child (Arliss, 1991). Sex role stereotypes are well established in early childhood. Messages about what is appropriate based on gender are so strong that even when children are exposed to different attitudes and experiences, they will revert to stereotyped choices (Haslett, Geis, & Carter, 1992).”

The stereotypes put forth by parents are then echoed in media – commercials, ads, children’s programs – and by the strangers and society in which the children interact.

But, you can work against these influences:

“Families with one or more androgynous parent (i.e., a mom who repairs the family car or a dad who bakes cookies for the PTA meeting) have been found to be highest on scores of parental warmth and support. These androgynous parents are found to be highly encouraging regarding achievement and developing a sense of self worth in sons and daughters (Sedney, 1987; Spence & Helmreich, 1980). Because of the strong influence of parents on gender role socialization, those parents who wish to be gender fair and encourage the best in both their sons and their daughters would do well to adopt an androgynous gender role orientation and encourage the same in their children.”

As you can probably guess, I have a huge problem with early assignment of gender stereotypes. I am desperately trying to avoid such labeling with my baby. It is a difficult battle. Grandparents on both sides want to know “what the baby is” so that they can go out and buy appropriate products. I have told them that the baby won’t care and that I like blue and green, but they just cannot bring themselves to purchase such things for a potentially girl baby. And I know that this request has to be easier than trying to get them to accept flowers or pink for any potential grandson.

I really want to know the gender of the baby. To me it is one more little piece of information. The nursery will be blue and green no matter what. I will buy cool gender neutral toys no matter what. But I do like certain traditionally male and female names, and I just want to know my baby that much better. I am very afraid, however, of telling this information to the grandparents in the fear that they will begin the process of stereotyping that I am trying so hard to avoid. I don’t care if strangers know if my baby is a boy or a girl. In fact, I’d rather they didn’t. I don’t like pink and ruffles, so I don’t want the baby dressed in pink and ruffles. If later my child decides that he or she likes pink and ruffles, then that will be fine. I just don’t like the idea of this poor baby’s future being set up before it is even born. Now how do you tell that to your parents? Or worse, your husbands’?

If anyone is reading this, please tell me some good tips on how to avoid gender stereotyping pressures from grandparents. I could really use some advice.

PS
Some tips from Parents.com on how to minimize gender stereotyping in your child

• Worry less about what other people think. Focus more on your child’s individual abilities and needs and fret less about whether he’ll get teased for his choices. For instance, if you son wants to take dance class, don’t let fear of teasing stop you from signing him up.

• Avoid making stereotypical statements. Saying thing like, “Big boys don’t cry” or “Little girls shouldn’t get their pretty clothes dirty” may seem harmless (after all, our parents likely said these same things to us) but they do perpetuate unhealthy gender stereotypes.

• Make a conscious decision about what you want your child to play with. For example, are dolls okay for boys? Toy cars fine for girls? Guns off-limits regardless of gender?

• Minimize emphasis on appearance and maximize emphasis on skills, abilities, and personality traits. “Girls get more comments on appearance than anything else,” says Dr. Crowley-Long. “Be sure to recognize your daughter’s achievements and abilities. Compliment not just on how something looks but on the content.” An example: If your daughter shows you a drawing or book report she’s completed, instead of just complimenting how nice it looks say something like, “Wow. I can see you really put a lot of thought into that.”

• Try to separate girls from the media’s messages about their bodies. Because of pervasive media messages, most women feel they are too fat, too skinny, too flat-chested, too something. There’s nothing wrong with caring about your appearance, says Dr. Crowley-Long, but it shouldn’t be the most important factor in a girl’s or woman’s life. Assure your daughter that she looks great just the way she is, but also emphasize how great (smart, funny, kind) she is on the inside as well.

• Encourage girls to get involved in sports or musical performance. Boys tend to join these activities more than girls as they get older, so girls may be missing out on some of the benefits. Research shows that involvement in sports, for example, can boost a child’s confidence and lower her likelihood of body image problems.

• Monitor your child’s media consumption. Be aware of what your kids are watching and listening to and the messages they are getting. Talk to them about what they are hearing and seeing.

Am I a Woman or a Scientist?

admin February 7th, 2008

Things that I notice, but maybe I shouldn’t

1. We frequently have visitors to our lab. We know who the important ones are because my advisor makes them up a schedule that usually includes each one of the group members talking to the visitor for about 15 minutes about our (published) work. I have also been asked to show various visitors around, take pictures, etc. Almost every time I introduce myself or am introduced as a PhD candidate, they react with what seems to be both enthusiasm and surprise. Now, this might be very normal. This might happen to all the other students these visitors meet. Maybe they are always surprised at finding PhD students in a research lab. Somehow, I don’t think so. So I am left wondering what it is about me that makes them so surprised. Is it because I am a woman? Do I look exceptionally young? Is it because I am in the severe American minority in our group? I used to never identify myself as a woman, or American, scientist. But now that I am in a minority I find myself doing this all the time and I have to wonder if I was just incredibly naïve before, or am I aligning myself across divisions that aren’t really there?

2. Every few months we have a lunch to celebrate good news, invite new members to the group, and say goodbye to departing ones. Personal information about various group members is also mentioned. Recently we had a lunch in which two male members were mentioned because they were happy to have their wives coming over from their home country. We have also had celebrations of new marriages, and a mention of one male member’s pregnant wife. I think this is great as it gives our rather large group a little appreciation of the alternate lives our members lead. So, I have to say that I was a little disappointed when mentions of people’s wives flying over were made, but nothing was said about my pregnancy. Maybe my advisor was trying to be discrete (though everyone knows) or maybe he thinks that I will find it too personal for him to bring up in that way. Those are both completely valid reasons. Still, I can’t help feeling that I am just not as important, or respected, or cared about than many other members in this group. If he can bring up a male member’s upcoming parenting status, why can’t he congratulate me on mine? Maybe I am just making something into a whole lot of nothing, but little things like this get to me.

Vote People

admin February 5th, 2008

I am feeling great this morning because I got up and instead of heading right to work, I went over to a nearby school and voted. To me this is a huge deal. This is me taking part in my government. This is me being counted. This is me thanking all of those thousands of people who died so that I could do this. Most of all, this is fun.

So I just can’t understand when people don’t even bother. Maybe I can see if in the presidential election you don’t feel like you count because, say, you are a Democrat and the rest of the state is overwhelmingly Republican. I don’t think that really gives you an excuse, but I can somewhat empathize. Thank you, electoral college. But in other elections, elections for Mayor and Governor, and Representatives, and new legislation, and the Presidential Primary how could you not even care? These things affect you, people!

My rant stems from a conversation I just had with a colleague who told me that she wasn’t even sure if she was registered. Not registered? Not sure? What? I don’t care who you vote for. I don’t care if you vote for someone I hate who I think will utterly ruin the country. In fact, many people did just that at the last presidential election. All those very misguided people I hold with so much higher respect than the people who could not get off their duffs, wait a few minutes and punch a screen. Just vote, people.

And if you don’t, you should be ashamed.

Happiness Is

admin February 4th, 2008

Listening to your favorite songs on your ipod, feeling the baby kick, working on your thesis, advisor out of town.